PRE-FORMULATION SERVICES
Pre-Formulation Solutions
Comprehensive analysis to understand and optimize drug substance properties
CorePharma provides advanced pre-formulation services focused on gaining a deep understanding of the physicochemical properties of active pharmaceutical ingredients (APIs). These early-stage studies are essential for designing robust and effective formulations, ensuring that every product begins with a strong scientific foundation aligned with its intended therapeutic performance.
Our team evaluates critical parameters such as solubility, dissolution behavior, stability under various environmental conditions, particle size distribution, and solid-state characteristics. This detailed analysis allows us to identify potential formulation challenges at an early stage and define the most appropriate development strategy for each molecule.
By applying a data-driven and systematic approach, we help reduce development uncertainties, enhance formulation efficiency, and support seamless scale-up into manufacturing. Our insights ensure improved product consistency, performance, and long-term stability across different dosage forms.
CorePharma also conducts comprehensive compatibility studies and analytical evaluations to ensure that APIs interact effectively with selected excipients. This enables the development of safe, stable, and regulatory-compliant pharmaceutical products ready for further clinical and commercial advancement.
Physicochemical characterization of APIs
Solubility, stability, and compatibility studies
Particle size and solid-state analysis
Optimized for scalable and regulatory-ready development